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Symbol
Name
ID

Tcf4
transcription factor 4
MGI:98506

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Esophagitis	Keratitis
Disease(s) Associated with TCF4	Esophagitis	Keratitis
Fuchs' endothelial dystrophy
Pitt-Hopkins syndrome

Mouse Phenotypes		immune system phenotype	decreased thymocyte number	abnormal B cell differentiation	decreased pro-B cell number	abnormal T cell differentiation	increased double-negative T cell number	decreased double-positive T cell number	spleen hypoplasia	abnormal T cell physiology
Availability	Mouse Genotype	immune system phenotype	decreased thymocyte number	abnormal B cell differentiation	decreased pro-B cell number	abnormal T cell differentiation	increased double-negative T cell number	decreased double-positive T cell number	spleen hypoplasia	abnormal T cell physiology
	Tcf4^tm1.1Hmb/Tcf4^tm1.1Hmb	*
	Tcf4^tm1Zhu/Tcf4^tm1Zhu
	Tcf4^tm1.1Hmb/Tcf4⁺
	Tcf4^tm1Hmb/Tcf4^tm1Zhu Tg(Kit-cre)143Hmb/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23